Complement-Fixation Technique: II. THE TITRATION OF WASSERMANN ANTIGEN

Complement-Fixation Technique: II. THE TITRATION OF WASSERMANN ANTIGEN.

After material has been produced for use as an antigen in a complement fixation test it is necessary to find out if the finished product has any complement-fixing ability in the presence of a serum containing a suitable antibody. Moreover, the proposed antigen must not have any undue anticomplementary property, and the " gap" between its anticomplementary titre and its complement fixing titre m...

An investigation into the use of cardiolipin antigens. II. Complement-fixing properties of cardiolipin Wassermann antigen.

Complement-Fixing Properties of Cardiolipin This reagent was examined using two ranges of 0-6 per cent. to 0 0045 per cent. One range was suspended in saline at a dilution of 1 in 50 and the other at 1 in 200. No fixation of complement was obtained when using syphilitic sera. Mixtures of cardiolipin and lecithin were next tested for their complement-fixing ability in the presence of a suitable ...

An examination of the treponemal Wassermann reaction and Reiter protein complement-fixation test.

Less than one year after the description of the Treponema pallidum by Schaudinn and Hoffman, the first report of the application of the complementfixation reaction of Bordet and Gengou (1901) to the diagnosis of human syphilis was published in Budapest by Detre (1906), exactly 2 weeks after the appearance of the classical paper "A Sero-diagnostic Reaction in Syphilis" by Wassermann, Neisser, an...

An Examination of the Treponemal Wassermann Reaction and Reiter Protein Complement-fixation

Less than one year after the description of the Treponema pallidum by Schaudinn and Hoffman, the first report of the application of the complementfixation reaction of Bordet and Gengou (1901) to the diagnosis of human syphilis was published in Budapest by Detre (1906), exactly 2 weeks after the appearance of the classical paper "A Sero-diagnostic Reaction in Syphilis" by Wassermann, Neisser, an...

Automation of the Wassermann complement-fixation test using a discrete analyser.